Spinal somatosensory evoked potentials in hereditary spastic paraplegia.

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Spinal somatosensory evoked potentials in hereditary spastic paraplegia.

Cervical somatosensory evoked potentials elicited by median nerve stimulation were recorded from 18 cases of hereditary spastic paraplegia. Motor and sensory nerve conduction in the median nerve was normal in each. In one third of the patients no spinal evoked potential was detectable. In the remainder the amplitude of the evoked potential was reduced in comparison with a control series; the la...

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Hereditary spastic paraplegia.

Hereditary spastic paraplegia (HSP) or Strümpell-Lorrain syndrome is a heterogeneous group of inherited disorders, with prevalence ranged from 4.3 to 9.6 cases per 100,000 population. A common feature of these disorders is the slowly progressive and often severe spasticity, noticeably especially in the low limbs. Conventionally, HSP is divided into two clinical groups, uncomplicated (pure spast...

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Hereditary Spastic Paraplegia.

111 families, and Paskind and Stone (1933) also summarized the literature with accounts of another 36 reports from 40 families. Since then about 50 further reports have appeared, covering some 60 families, bringing the total so far to 176 reports of 215 families. Of these the majority have originated in Germany or elsewhere in Europe, but with a substantial number from the Americas. In Britain,...

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Somatosensory evoked potentials during spinal surgery.

A L T H O U G H anaesthetists routinely use a myriad of monitors to assess the integrity of many organ systems, we do not commonly monitor the nervous system. During many operative procedures nervous tissue is placed at considerable risk of injury yet, for the most part, continues to go unmonitored. One of the most common operative procedures which places nervous tissue at risk is spinal surger...

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SPG3A gene polymorphisms in hereditary spastic paraplegia

Objective: This study aimed to analyze the hereditary spastic paraplegia (HSP)/spastic paraplegia 3A (SpG3A) genomic structure as well as the polymorphisms in SPG3G genomic structure by comparing with the normal subjects. Methods: A total of 66 sporadic cases with HSP were collected from April 2014 to September 2016. Genomic DNA extraction was performed, and all coding exons and junction region...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1981

ISSN: 0022-3050

DOI: 10.1136/jnnp.44.3.243